Symptoms of diseased kidneys on the skin and urine!
Today I’m going to talk to you about the symptoms of kidney disease. It is always important to recognize the disease in the early stages of the disease because then it is much better treated. The kidneys are paired organs the size of a fist, located on both sides of the spine under the rib arches. You probably know that they are the “filters” of all the blood that passes through the body, but besides that, they also have many other functions important for the health and normal functioning of our entire organism. The kidneys are closely related to other vital organs such as the heart, lungs or liver, and their good “communication” maintains a healthy balance of blood volume, electrolytes and dynamics of the whole organism.
Kidneys are very interesting organs, primarily due to the fact that only 10% of their mass can be functional, without presenting the symptoms of their disease or they are nonspecific, and therefore neglected. Also, the kidneys are very effective in dividing and organizing work – if one kidney or some part of it cannot perform its function well for any reason, the rest of that same kidney or the other one takes over its work very effectively. In this way, important physiological parameters such as blood pressure and blood volume remain normal, and waste products are still effectively expelled from the body. And as I mentioned, the liver, lungs, heart and kidneys are one very important mechanism.
Each kidney consists of about a million building units called nephrons
Nephrons can be called “microscopic filters” because each of them performs the task of filtering blood. Each nephron is made up of two parts: a tangle of capillaries called a glomerulus and a tubule system( tube). Blood filtration begins with the blood flowing to the glomeruli in which larger particles, such as erythrocytes and proteins, are filtered out by the kidneys, and when the kidneys are functional, they are able to filter out harmful toxins from the body. In some parts there is a reabsorption (return to the blood) of glucose, in some to the reabsorption of sodium, potassium and other electrolytes, depending on what the body needs at that moment. You may not have known it, but your kidneys are also hormone producers. The first of these is erythropoietin or hematopoietin, a hormone that stimulates the production of red blood cells (erythrocytes) in the bone marrow. This hormone is very important in maintaining a normal blood count and ensures that the body has a sufficient amount of erythrocytes and hemoglobin. Hemoglobin is a molecule found in red blood cells, and its task is to bind and transport oxygen to all cells in the body.
The kidneys also produce the hormone renin, which is crucial for regulating blood volume and pressure.
When this pressure is lowered, and this means that there is less blood flow through the kidney, these cells begin to secrete renin. Renin goes into circulation and further stimulates a cascade of events that results in an increase in blood pressure and an increase in circulating blood volume. In this way, the kidneys can very effectively regulate the level of blood pressure and blood volume. The biologically active form of vitamin D is called calcitriol, and it is actually one of three homons produced by the kidneys. Therefore, it is correct for vitamin D to say that it is a hormone, not a vitamin. However, for ease of understanding, the name vitamin is still used. The kidneys play an important role in maintaining the water balance in the body. Water can enter the body through the consumption of food and drink, and a small percentage of water is produced as a product of various metabolic processes in the body. On the other hand, water comes out of the body through sweating, breathing, defecation, but mostly through urination.
The first symptom of kidney disease is CHRONIC FATIGUE. A serious decrease in kidney function can lead to the accumulation of toxins and impurities in the blood. This can cause people to feel tired, weak, and can make it harder to concentrate. Another complication of kidney disease is anemia, which can cause weakness and fatigue.